Hedgehog signaling is required for many aspects of development in vertebrates and invertebrates.Misregulation of the Hedgehog pathway causes developmental abnormalities and deroyal finger spring has been implicated in certain types of cancer.Large-scale genetic screens in zebrafish have identified a group of mutations, termed you-class mutations, t
Although structurally and skincure cream biochemically similar to the cellular prion (PrP(C)), doppel (Dpl) is unique in its biological functions.There are no reports about any neurodegenerative diseases induced by Dpl.However the artificial expression of Dpl in the PrP-deficient mouse brain causes ataxia with Purkinje cell death.Abundant Dpl prote
Abstract Background Community health workers (CHWs) can support patient engagement in care for a variety of health conditions, including HIV.This paper reports on the experiences of HIV clinics and health departments that integrated CHWs into their health systems as part of a capacity-building initiative to address HIV-related disparities in the Un